celiac disease manifesting with deep venus thrombosis: a case report

celiac disease has protean manifestations. in this report, a 24 year-old young female with celiac disease and acute lower extremity deep venous thrombosis (dvt) is presented. the patient was a 24 year-old female who presented with long standing diarrhea, 8 kg weight loss in the recent month, lower extremity edema, petechiae and purpura. laboratory exam demonstrated very high titers of iga antiendomysial antibody and igaanti-ttg plus a positive histology. doppler sonography revealed the presence of acute dvt in common femoral vein expanding towards distal. due to increased pt and ptt and protein c deficiency, vitamin k deficiency as a consequence of celiac disease was suggested. with the initiation of gluten free diet, vitamin k replacement and anticoagulant therapy, symptoms resolved in few days. six months later, she had a weight gain of 20 kg. it is highly recommended to evaluate patients with chronic diarrhea,weight loss and dvt for celiac disease markers.